Chinese scientists have become the first to complete the
genome-sequencing of the severe acute respiratory syndrome (SARS)
virus.
The breakthrough was achieved by the Beijing Genomics Institute of
the Chinese Academy of Sciences (CAS), which cooperated with the
Microbe Epidemic Institute of the Military Medicine Academy of
Sciences.
On
April 16, the World Health Organization (WHO) officially identified
the coronavirus as the cause of SARS. On this basis, scientists
from both organizations also joined hands and efforts with Xie He
Hospital and other clinics, successfully developing a specific
enzyme link immunoabsorbent assay for rapidly testing SARS.
Kang Le, director of the biological bureau of the CAS, said this
specific assay would be mainly developed and produced at the
Beijing Genomics Institute.
Dr. Dong Wei, with the institute's genotyping group, said the test
has been put into use at all Beijing's designated hospitals for
SARS, and in one week, it could meet all of the country's
requirements.
Yang Huanming, director of the Beijing Genomics Institute, said the
assay is accurate, sensitive, rapid, and convenient as well as
economical. One assay plate can test a total of 96 samples at the
same time.
Most importantly, Yang said, the results can be known after one
hour.
Scientists said once people get infected with SARS, their body
would produce specific antibody-countering virus proteins. The way
the test works is these virus proteins combine with specific
antibodies and, through the enzyme link reaction, the assay changes
color, showing the virus is present.
Experts pointed out that the test will provide an accurate,
reliable and rapid as well as economical diagnosis means for
controlling the disease's spread. It will also play an important
role in the prevention and diagnosis of SARS.
(Xinhua News Agency April 23, 2003)
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